Intermittent Dialysis Leading to Dialysis Disequilibrium Syndrome

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Dialysis Disequilibrium Syndrome

A aggressive dialysis in a grossly azotemic patient, especially one with severe metabolic acidosis, can lead to dialysis disequilibrium syndrome (DDS). Mild forms present as nausea, vomiting, restlessness, and headache. Severe manifestations include seizures, obtundation, coma, and even death. This clinical picture is caused by cerebral edema induced by one or more of the following mechanisms:

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Sepsis and Dialysis Disequilibrium Syndrome

Dialysis disequilibrium syndrome (DDS) is a central nervous system disorder, usually occurs in patients during hemodialysis (HD) or within 24 hours of HD. DDS was first described by Kennedy et al. in 1962. 11 If a critically ill patient on HD develops severe sepsis and septic shock with multiple organ failure (MOF), the adverse effect of HD on the brain is likely to be amplified, which may pred...

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Dialysis Disequilibrium Syndrome: A Neurological Manifestation of Haemodialysis

Renal insufficiency has many protean effects on the central nervous system. Early symptoms such as fatigue, clumsiness, and impaired concentration may progress to hallucinations, agitation, disorientation and coma if the renal insufficiency is untreated. The pathophysiology of these changes, due to uraemic encephalopathy are thought to be mediated by impaired neurotransmission (Burn & Bates, 19...

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Dialysis Disequilibrium Syndrome: The Changes of Intracranial Pressure

Dialysis Disequilibrium Syndrome (DDS) is a rare but well-known serious complication of dialysis [1]. A clinical deteriorated neurological symptom due to cerebral edema after hemodialysis is defined as the dialysis disequilibrium syndrome, which is similar to symptom that occurs with increased Intracranial Pressure (ICP) [2]. However, the direct evidence of increased ICP is rarely described in ...

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Dialysis disequilibrium syndrome occurring during continuous renal replacement therapy

The dialysis disequilibrium syndrome (DDS) is characterized by progressive neurological symptoms and signs attributable to cerebral edema that occurs due to fluid shifts into the brain following a relatively rapid decrease in serum osmolality during hemodialysis (HD). Since continuous renal replacement therapy (CRRT) is less efficient at solute clearance than intermittent HD, it seems logical t...

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ژورنال

عنوان ژورنال: World Journal of Nephrology and Urology

سال: 2015

ISSN: 1927-1239,1927-1247

DOI: 10.14740/wjnu228e